| abstract |
The present invention relates to benzimidazole compounds as kinase inhibitors, and preparation methods and applications thereof. In particular, the present invention relates to benzimidazole compounds represented by general formula(I), their preparation methods and pharmaceutical compositions, and their applications as kinase inhibitors in the preparation of drugs. The drugs can prevent and / or treat diseases related to cancer or tumor, especially bladder cancer, ovarian cancer, peritoneal cancer, pancreatic cancer, breast cancer, uterine cancer, cervical cancer, endometrial cancer, prostate cancer, female genital tract cancer, testicular cancer, gastrointestinal stromal tumors, and are expected to develop into a new generation of benzimidazole compounds as kinase inhibitor drugs. Each substituent in the general formula (I) is defined as that in the specification. |