| abstract |
Substituted benzoxaboroles whose structure comprises Formula Ill, n nwherein R 3 is selected from -CH 3 , -CH 2 CH 3 , -CH 2= CH 2 , -CH 2 CH 2 CH 3 , -CH(CH 3 ) 2 , -CH 2 CH 2= CH 2 , and cyclopropyl, R 1 and R 2 are each independently selected from H, -CH 3 , -CH 2 CH 3 , -CH 2 CH 2 CH 3 , and -CH(CH 3 ) 2 ; compositions containing such compounds, their use in therapy, including their use as anti-mycobacterial agents, for example in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds, are provided. |