| abstract |
A percutaneous microneedle monitoring system has a substrate, a microneedle unit, a signal processing unit, and a power supply unit, wherein the microneedle unit is formed by stacking a plurality of metal sheets with protruding microneedle arrays on the substrate , Each sheet is provided with at least one perforation, and the perforation edge is provided with a spur. The perforation on one of the sheets allows the spurs of the perforation edges at opposite positions on the remaining sheets to pass through, and the spurs are separated from each other, and the microneedle The unit can be equipped with a signal processing unit to continuously detect the concentration changes of various analytes appearing in the tissue fluid; in addition, it can also fix the drug sensing molecules on the protruding inner surface of the microneedle unit. It directly touches skin cells, so it is protected and intact. |