http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I729406-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e54d07fe8c2b4403b27798dc534adb05 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4196 |
filingDate | 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_756069ac90863b557bf140bdf9fc4309 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98b6390d2fe2c2afc83e89d2b464ea27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a83d909c6740fef513e13cf8deda217 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff8f12084a49c2f584dbcc84d5b3611e |
publicationDate | 2021-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-I729406-B |
titleOfInvention | Synthesis of 1,2,4-triazole derivatives as anti-inflammation substance and use thereof |
abstract | Novel synthesis of 1,2,4-triazole derivatives as the anti-inflammation substance is disclosed in the present invention. An efficient green method was developed for the synthesis of multi-substituted 1,2,4-triazoles with good yields from nitrilimines including amination and heterocyclization two steps reactions. 1,2,4-triazole derivatives were observed significant anti-inflammatory effects by inhibiting NO in LPS-induced RAW 264.7 cells, which can be used to develop various inflammatory drugs for treating related diseases. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I754474-B |
priorityDate | 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.