| abstract |
The present invention provides a double-layer membrane microcell (bicelles) structure composition, which can be safely and simply prepared without using an organic solvent, and has a sense of use as an external agent for skin (permeation, moisturizing, firmness) Excellent, and storage stability is also excellent.nn n n The present invention provides a composition containing a double-layer membrane microcellular structure, which is characterized by containing the following components (a) ~ (e): (a) phospholipids; (b) cholesterol and/or physterol 0.02~1 Mass%; (c) at least one selected from polyoxyethylene cholesteryl ether and/or polyoxyethylene phytosteryl ether with an average added molar number of ethylene oxide of 10-20 Surfactant; (d) a glycol selected from at least one of propylene glycol, dipropylene glycol, and 1,3-butanediol; (e) water; the mass ratio of the aforementioned component (a) to component (c) (a)/(c) is 0.4~2.0, the total of component (a) and component (c) is relative to the content of component (b)nThe ratio {(a)+(c)}/(b) is 5.0 or more. |