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filingDate 2010-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f53f55b8dffa0d3ab5e3a89306e7e989
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publicationDate 2021-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TW-I724448-B
titleOfInvention Method for the production of a glycosylated immunoglobulin
abstract Herein is reported a method for the production of an immunoglobulin comprising the following steps: a) providing a eukaryotic cell comprising a nucleic acid encoding the immunoglobulin, b) cultivating the eukaryotic cell in a cultivation medium wherein the amount of glucose available in the cultivation medium per time unit is kept constant and limited to less than 80 % of the amount that could maximally be utilized by the cells in the cultivation medium per time unit, and c) recovering the immunoglobulin from the culture.
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