| abstract |
The purpose of the present invention is to provide a compound with excellent JAK1 inhibitory effect. Since the compound of the present invention has JAK1 inhibitory activity, it has immunosuppressive effect, anti-inflammatory effect, proliferation inhibitory effect, etc., such as rheumatoid arthritis, inflammatory bowel disease, psoriasis, vasculitis, bronchial asthma, chronic obstructive pulmonary disease, The treatment of eosinophilic sinusitis and nasal polyps is more useful. |