abstract |
The present disclosure provides pharmaceutically acceptable salts, crystalline forms and preparation method of azabicyclo substituted triazole derivatives. In particular, the present invention provides a compound of formula A, 1-(2-chloro-4-fluorophenyl)-3-(5-(methoxymethyl)-4-(6-methoxypyridin -3-yl)-4H-1,2,4-triazol-3-yl)-3-azabicyclo[3.1.0]hexane. Compared with free hydrazine, the pharmaceutically acceptable salts of the compound has higher purity and more excellent chemical stability, and is of great significance for developing medicine suitable for industrial production and of good biological activity. |