abstract |
The invention provides a 4-1BB antibody and a preparation method and application thereof. Specifically, the present invention provides a 4-1BB antibody, which has high affinity for 4-1BB protein, can effectively initiate downstream signals of 4-1BB, and significantly increases IFN-γ in human mixed lymphocytes or T lymphocytes And the expression level of IL-2 can be used to treat cancer and autoimmune diseases. |