| abstract |
The present invention relates to a compound represented by following general formula (III), the compound’ s tautomer, stereomer, or pharmaceutical accpetable salts, or solvate thereof , as a treating agent for gout or hyperuricemia. n n n(wherein, R 1a , R 2a , R 6a and R 7a represent a hydrogen atom, an alkyl having carbon numbers of 1~8, an alkoxy having carbon number 1~8, cyame and the like, R 3a and R 8a together with the 2 carbon atoms to which R 3a and R 8a are bonded form a benzene ring or a 5-membered heteroaryl ring containing 1~3 hetero atoms selected from nitrogen atom, oxygen atom or sulfur atom, R 4a and R 5a together with the 2 carbon atoms to which R 4a and R 5a are bonded form a benzene ring, or have the same meaning as the above R 1a , X a represents an oxygen atom or a sulfur atom and the like, Y a represents an alkylene chain having a carbon numbers nof 1~8, wherein, the alkylene chain may be a linear alkylene chain or a branched alkylene chain, and the branched alkylene chain may form a 3-~7-membered ring by combining the side chains which are bonded to the same or different carbon atoms, together with the carbon atom bonded thereto, and may have double bond existing within the chain, Z a represents CO 2 H and the like.) |