abstract |
The invention is a method for modifying a pegylated substance, which comprises (1) providing a pegylated substance; (2) mixing the pegylated substance with a bifunctional antibody to obtain a mixture, wherein the The bifunctional antibody includes a first antigen-binding site that binds to polyethylene glycol; and a second antigen-binding site that binds to a target ligand; and (3) collecting the mixture. |