| abstract |
The present invention relates to an acrylic derivative represented by the formula (I), a stereoisomer thereof, a tautomer thereof or a pharmaceutically acceptable salt thereof, a process for producing the same, a pharmaceutical composition containing the same, and the like Therapeutic agents, particularly as a selective estrogen receptor down-regulator (SERD), wherein R 1 , R 2 , R 3 , R 4 in the formula (I) are as defined in the specification. |