abstract |
A sprayable aqueous pharmaceutical composition comprising glastron or such pharmaceutically acceptable salts, and a pharmaceutically acceptable inactive ingredient, comprising a tonicity agent, a preservative, and having bioadhesive properties and/or capable of being based on ions, pH A water-soluble polymer whose value and temperature change rheological behavior. This composition is administered intranasally to a patient in need thereof for rapid treatment and/or prevention of nausea and/or vomiting caused by cytotoxic chemotherapy, radiation therapy or surgery. This composition has an advantage of being able to compare the rapid absorption and onset time of intravenous injection, prolonged drug plasma concentration and pharmacological action, and reducing nasal tingling and the like. |