http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I642787-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc06cad2b58bbfcc30e3c96a6eb6c926 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
| filingDate | 2013-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbfd97ebddfbb6447e909f6c844d87d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a80be106f04640d68c8cf27e9c1127d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e1298ea1b166460c1aa77758672fe34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68973539962ceb227086332b28ee69c3 |
| publicationDate | 2018-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-I642787-B |
| titleOfInvention | Use of a small ribonucleic acid Let-7g for anti-hepatitis C virus |
| abstract | The purpose of this case is to investigate the regulation and correlation of Let-7g in hepatitis C virus infection. Let-7g can effectively reduce the hepatitis C virus NS5B gene, core protein and viral load, and Let-7g combined with interferon / ribavirin also synergistically inhibited the expression level of hepatitis C virus. Let-7g binds directly to the hepatitis C virus gene to inhibit viral expression, and the effect of inhibiting the virus is also related to interferon/rebavirin. It was found in the samples that the expression level of Let-7g in the serum or liver tissues of the patients was significantly lower in the non-viral sustained reaction group before the treatment than in the patients in the virus continuous reaction group. This case proposes the pathogenesis of Let-7g in the hepatitis C virus infection, which can make Let-7g develop into a potential target for hepatitis C virus therapy. |
| priorityDate | 2013-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 181.