abstract |
The present invention provides a recombinant glycoprotein (e.g., a recombinant human alpha-galactosidase-A protein) having an altered (e.g., enhanced) glycosylation profile, and a pharmaceutical composition comprising one or more of these proteins Objects and sets. The invention also provides a method for producing a mammalian cell line for recombinantly expressing a glycoprotein (e.g., recombinant human alpha-galactosidase-A), a method for producing a recombinant glycoprotein, and administering to a patient at least one of these A method of treating a recombinant glycoprotein (eg, a recombinant human alpha-galactosidase-A protein). |