| abstract |
The present invention provides a binding polypeptide (eg, an antibody or a fragment thereof) that specifically binds to a target antigen (eg, a human antigen, such as human PDGFRβ) with high affinity. The invention also provides libraries of binding polypeptides, pharmaceutical compositions, as well as nucleic acids encoding binding polypeptides, recombinant expression vectors, and host cells for making such binding polypeptides. The invention also encompasses methods of using the binding polypeptides of the invention to diagnose and treat diseases. |