abstract |
In particular, the present invention provides a method for producing a blood protein composition from pooled plasma. In a specific example, the present invention provides an alcohol fractionation protocol that can significantly increase the yield of blood proteins purified from a starting plasma sample. In a specific embodiment, a method for fractionally separating and pooling plasma is provided, which method comprises an initial low pH, high concentration alcohol precipitation step. The invention also provides pharmaceutical compositions for therapeutic blood proteins. |