http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I624461-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_321b10c632ca3a14bdb685ff273c4f4c |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 |
| filingDate | 2013-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bb7b73e0a7b5e1d0c92b423edda4ffd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c973d3978d36fe030574d9120b428260 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81f702c1123da23cbe63744657470e04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a87163a45afc65801e21fceb17b5d5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a2c2e7a7df54e5ec0e28bf76f280527 |
| publicationDate | 2018-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-I624461-B |
| titleOfInvention | Quinazoline compound, preparation method and use thereof |
| abstract | A compound for treating a protein kinase-related disease having the structure of formula (I): Wherein G is heteroaryl, heterocyclyl or alkynyl; X is N or CH; L 1 is -N(R 7 )-, -O-, -C(S)-, -C(O)- or - S-; L 2 is -N(R 8 )- or -O-; R 1 and R 2 are each hydrogen, halogen, hydroxy, amine, cyano, nitro, carboxyl, C 1 -C 4 alkoxy , C 1 -C 4 alkoxy C 1 -C 4 alkoxy, N,N-(C 1 -C 4 dialkyl)amino C 1- C 4 alkoxy, N-(C 1 - C 4 alkyl)amino C 1 -C 4 alkoxy, C 1 -C 4 alkanoyl, C 1 -C 4 alkoxy, N-(C 1 -C 4 alkyl)amine, N An N-(C 1 -C 4 dialkyl)amino group, a C 1 -C 4 alkyl fluorenyl group or a heterocyclic group; wherein the C 1 -C 4 alkyl group may optionally be selected from one or more selected from the group consisting of fluorine and chlorine Substituted by a substituent; R 3 , R 4 and R 5 are each hydrogen, fluoro or chloro; R 6 is C 1 -C 4 alkyl or aryl, which may optionally be selected from one or more selected from the group consisting of halogen, hydroxy, Substituted with a substituent of an amino group, a cyano group and a nitro group; or R 6 and R 8 are selected from a 5-6 membered ring group or a heterocyclic group. |
| priorityDate | 2013-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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