| abstract |
The present invention relates to novel benzodiazepine derivatives having anti-proliferative activity, and more particularly, to novel benzodiazepine compounds of formulae (I) to (VII). The invention also provides a conjugate of a benzodiazepine compound and a cell binding agent. The invention also provides compositions and methods that can be used to inhibit abnormal cell growth or treat a proliferative disorder in a mammal using a compound or conjugate of the invention. |