| abstract |
The invention relates to imidazoline derivatives, a preparation method thereof, and its application in medicine. Specifically, the present invention relates to a novel imidazoline derivative represented by the general formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, and a therapeutic agent thereof, and particularly as an androgen receptor antagonist. And the use in the preparation of a medicament for treating diseases such as prostate cancer, wherein each substituent of the general formula (I) has the same definition as in the specification. |