abstract |
The invention relates to a highly concentrated long-acting human growth hormone conjugate liquid preparation and a preparation method thereof, the preparation comprising a pharmaceutically effective amount of long-acting human growth hormone conjugate (wherein human growth hormone (hGH) is connected to an immunoglobulin) Protein Fc region) and albumin-free stabilizer. The stabilizer includes a buffer, a nonionic surfactant, sugar alcohol, and sodium chloride as an isotonic agent. |