| abstract |
The present invention relates to a treatment method for preventing or treating thrombosis of diseases related to abnormal coagulation or fibrinolysis, using an IL-6 antagonist such as an antibody and a fragment thereof specific for IL-6. In a preferred embodiment, these patients will include those who exhibit elevated D-dimer or other coagulation-related proteins and selectively exhibit elevated C-reactive proteins before treatment. Such treatment may include administration of other actives such as chemotherapeutics, anticoagulants, statins, and the like. |