| abstract |
The present invention relates to novel 5'-substituted nucleoside compounds; pharmaceutical compositions comprising these compounds; and methods of using these compounds to treat cancer, and more particularly for the treatment of the following cancers in particular: neuroglioblastoma, Melanoma, sarcoma, gastric cancer, pancreatic cancer, bile duct cancer, bladder cancer, breast cancer, non-small cell lung cancer, leukemia and lymphoma including acute myeloid leukemia. |