| abstract |
The subject of the present invention is to provide a therapeutic agent and / or preventive agent for pain, or a therapeutic agent and / or preventive agent for diseases involving sodium channels.nn n n The solution of the present invention is to provide a compound represented by the following formula (I) or a pharmacologically acceptable salt thereof: n n n Ar 1 , Ar 2 : heteroaryl, aryl; R 1 , R 2 , R 3 : hydrogen atom, halogen atom, C1-C6 alkyl, halogenated C1-C6 alkyl, hydroxy C1-C6 alkyl, C1- C6 alkoxy C1-C6 alkyl or C3-C7 cycloalkyl, cyano; R 4 , R 5 : hydrogen atom, halogen atom, C1-C6 alkyl, halogenated C1-C6 alkyl, hydroxyl, hydroxyl C1- C6 alkyl, C1-C6 alkoxy C1-C6 alkyl, C3-C7 cycloalkyl, C1-C6 alkoxy; n: an integer from 1 to 3; heteroaryl and aryl may have 1 or 2 Independently selected from halogen atom, C1-C6 alkyl, halogenated C1-C6 alkyl, hydroxy, hydroxy C1-C6 alkyl, C1-C6 alkoxy C1-C6 alkyl, C3-C7 cycloalkyl, carboxyl, When there are two cyano, amine, C1-C3 alkylamino, and diC1-C3 alkylamino groups, they may be the same or different. |