http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I290133-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3d85238f30ab01379398800c900c6f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac3eca7fa2f8ecd6ea05588b14520fb4 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 |
| filingDate | 2005-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84d8474260ccce3dcdcb38559912d418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dd2e29af59f131fe45f56516e70918d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_475c865a346d67ce3c1bbedb5d18b897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cf52eb86bbd77e4e45f8ff03fd14b2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c736d29cc5c479ff8df52f9cdb2b7a14 |
| publicationDate | 2007-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-I290133-B |
| titleOfInvention | Process for preparation of tamsulosin and its aralkylamine derivatives |
| abstract | The present invention discloses a new process for the synthesis of tamsulosin and its aralkylamine derivatives, especially (R)-(-)-5-{2-[2-(2-alkoxyphenoxy) ethylamino] propyl}-2-alkoxybenzenesulfonamides having the following formula 1 (where R1 and R2 represent C1-C4 alkyl groups) and their hydrochloride thereof, and other various pharmaceutical used salts. Tamsulosin hydrochloride (R1=Et, R2=Me, in its hydrochloride salt form) is an antagonist of alpha-A adrenoceptors in the prostate. Tamsulosin HCl occurs as white crystals, which melt with decomposition at approximately 230 DEG C. It is sparingly soluble in water and in methanol, slightly soluble in glacial acetic acid and in ethanol, and practically insoluble in ether. |
| priorityDate | 2005-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 193.