http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I288751-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1cd42ae588d09d106d44d507d002992e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 |
| filingDate | 2001-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb2ea67578696c3809bef648e3eb3b82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_653fff5e7d714471ab8464813c86cabd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29a30fe5ea05f8d1bce78aa2e7bdc67a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30a17608b3ce7e7ad477807317c5745a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70a362edd565d65597508b30e148e23b |
| publicationDate | 2007-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-I288751-B |
| titleOfInvention | Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy |
| abstract | The present invention encompasses radiolabeled peptide analogs of el vasoactive intestinal peptide (VIP) labeled with a radionuclide useful for imaging target sites within mammalian living systems. The invention particularly provides radiolabeled VIP derivatives that bind selectively to the VIP receptors on target cells. Specifically, the invention relates to the radiolabeling of VIP-receptor specific agents and their subsequent use for radiodiagnostic and radiotherapeutic purposes. The invention encompasses methods for radiolabeling these peptide with radionuclides and the use of these peptides as scintigraphic imaging agents. The radiolabeled VIP derivatives of the present invention exhibit pharmacological activity and therefore are useful as either imaging agent for visualization of VIP-receptor positive tumors and metastases, as a radiodiagnostic agent or as a radiotherapeutic agent for the treatment of such tumors in vivo by specifically targeting the cytotoxic radionuclide selectively to the tumor site in mammalian living systems. |
| priorityDate | 2000-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 429.