abstract |
The present invention relates to a method for the preparation of compositions, preferably pharmaceutical compositions, in form of expanded, mechanically stable, lamellar, porous, sponge-like or foam structures out of solutions and dispersions. This method comprises the steps of (a) preparing a solution or a homogeneous dispersion of a liquid and a compound selected from the group consisting of one or more pharmaceutically active compounds, one or more pharmaceutically suitable excipients, and mixtures thereof, followed by (b) the expansion of the solution or the homogeneous dispersion without boiling. The invention also relates to the compositions, their further processing and any corresponding dosage forms obtainable by the above method. |