| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1676
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B29B9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate |
2004-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2007-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67747b152418db571c45700b5ed92075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4e4c4e7666dc815fb80609770c3f518
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_797b810b6146fca1e5ff932b59e0bc7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96fbc531a4a8363b9caa3348f5c5db3b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d68990d50be7a74c56ff788889322090 |
| publicationDate |
2007-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-I270380-B |
| titleOfInvention |
Azithromycin multiparticulate dosage forms by liquid-based processes |
| abstract |
Liquid-based processes are disclosed for forming azithromycin multiparticulates having minimal amounts of azithromycin esters. A liquid-based process for the formation of multiparticulates comprising the steps: (a) forming a mixture comprising azithromycin, a pharmaceutically acceptable carrier, and at least one liquid having a boiling point of less than about 150 C; (b) forming particles from said mixture of step (a) by a method selected from (i) atomization of said mixture, and (ii) coating seed cores with said mixture; and (c) removing a substantial portion of said liquid from said particles of step (b) to form said multiparticulates wherein the following expression is satisfied: [A] <= 0.04/(1-x), where [A] is the concentration of acid/ester substitution on the carrier in meq/g azithromycin, and x is the weight fraction of the azithromycin in said multiparticulates that is crystalline. |
| priorityDate |
2003-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |