http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I255721-B

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a8c9ac69b5ea19c0d4353dee5d92b3b
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filingDate 1999-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2006-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d358a8b40e30c31ae68d2cea403c259
publicationDate 2006-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TW-I255721-B
titleOfInvention Absorbable microparticles
abstract This invention pertains to a sustained release complex of one or more peptide, one or more protein or a combination thereof immobilized on an absorbable polymer microparticle optionally having an absorbable polymer coating. The microparticle complex of this invention comprises a peptide(s) and/or protein(s) which have at least one amino group and/or at least one carboxyl group per molecule and a solid absorbable polyester microparticle having surface and subsurface carboxylic groups or amino groups in sufficient amounts to bind the peptide(s) or protein(s) represent 0.1% to 30% of the total mass of the microparticle complex. The microparticle complex with immobilized peptide(s) and/or protein(s) are optionally further encased individually or in groups with an absorbable polymer to control, further, the release of the immobilized peptide(s) and/or protein(s). To control the release of the immobilized peptide(s) and/or protein(s) even further, the encased microparticles can be incorporated into a composition with an absorbable gel-forming liquid that transforms to a flexible gel or semi-solid upon contacting water in the biologic environment.
priorityDate 1998-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 29.