abstract |
A class of benzopyrans, benzothiopyrans, dihydroquinolines, dihydronaphthalenes, and analogs thereof, is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by formula I', wherein X, A1, A2, A3, A4, R, R"", R1 and R2 are as described in the specification. |