http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I222976-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-0076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-0015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02 |
| filingDate | 1993-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0954dc7f31391fef75ab62590b52d3ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9245f45557bb70baccfceb8f5dd410ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faf3d1684bca05831b55574465be2d7f |
| publicationDate | 2004-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-I222976-B |
| titleOfInvention | New preparation process for 16 alpha-methyl steroids |
| abstract | The invention relates to a new process for preparing compounds of formula (I); R. in which rings A and B represent a 3-keto-Delta4-6-R3, remainder, optionally in the protected form in position 3, or 3-keto-Delta1,4-6-R3 remainder, R is methyl or -CH2OR' where R' is hydrogen or an ether or ester remainder, R1 and R2 form an epoxide in position beta, a second bond, or R1 is hydrogen, ketone, or hydroxy in position alpha or beta, optionally in etherified or esterified form, and R2 is hydrogen, or R1 is hydrogen and R2 is alpha-hydroxy, or R1 is beta-hydroxy optionally etherified or esterified and R2 is a fluorine or a bromine in position alpha, R3 is hydrogen, fluorine or methyl in position alpha or beta, according to which a 16(17) derivative is treated with a methylation agent, then the intermediate is hydrolyzed and the enol so obtained is oxidized with molecular oxygen in the presence of an appropriate reducing agent. The compounds (I) are known anti-inflammatory agents or possible precursors. |
| priorityDate | 1992-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.