| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8be6a6c990669567cc455d32b00535e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-08 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-33 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-92 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-295
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-08 |
| filingDate |
1998-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa398aa12cb875c3eed62af8cf722ff0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e90d22daf826d12d2bfebfaaafac31a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ce0d5ff4ed486001cbe79c30618c665
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1053f9d54805d0e44239f956e67c2a3c |
| publicationDate |
2004-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-I221847-B |
| titleOfInvention |
Clostridium perfringens vaccine |
| abstract |
The present invention relates to detoxified immunogenic derivatives of Clostridium perfringens beta-toxin or an immunogenic fragment thereof that have as a characteristic that they carry a mutation in the beta-toxin amino acid sequence, not found in the wild-type beta-toxin amino acid sequence. The invention also relates to genes encoding such beta-toxins, as well as to expression systems expressing such beta-toxins. Moreover, the invention relates to bacterial expression systems expressing a native beta-toxin. Finally, the invention relates to vaccines based upon detoxified immunogenic derivatives of Clostridium perfringens beta-toxin, and methods for the preparation of such vaccines. |
| priorityDate |
1997-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |