abstract |
An inorganic ion receptor modulating compound having the formula: wherein Ar1 is either naphthyl or phenyl optionally substituted with 0 to 5 substituents each independently selected from the group consisting of, lower alkyl, halogen, lower alkoxy, lower thioalkyl, methylene dioxy, lower haloalkyl, lower haloalkoxy, OH, CH2OH, CONH2, CN, acetoxy, N(CH3)2, phenyl, phenoxy, benzyl, benzyloxy, alpha,alpha-dimethylbenzyl, NO2, CHO, CH3CH(OH), acetyl, ethylene dioxy; Ar2 is either naphthyl or phenyl optionally substituted with 0 to 5 substituents each independently selected from the group consisting of, lower alkyl, halogen, lower alkoxy, lower thioalkyl, methylene dioxy, lower haloalkyl, lower haloalkoxy, OH, CH2OH, CONH2, CN, and acetoxy; q is 0, 1, 2, or 3; and R is either H, lower alkyl; and pharmaceutically salts and complexes thereof; wherein said compound modulates one or more inorganic ion receptor activities. |