http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-568786-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_634715a790f7ef0163a61e9f364bebcd |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 |
| filingDate | 1998-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa9c3507a41ffcb4ac5e44bda87b3d11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_434b354b9f3c182e8d4c6fd0be1e56dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7448b92ab8a6d703d7cc6bb9eda9dfa6 |
| publicationDate | 2004-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-568786-B |
| titleOfInvention | A combination, pharmaceutical formulation, and kit for use in the treatment of affective disorders |
| abstract | The invention relates to a combination of a first component (a) which is a selective 5-HT1A receptor antagonist having the formula I wherein R1 is n-propyl or cyclobutyl, R2 is isopropyl, tertiary butyl, cyclobutyl, cyclopentyl or cyclohexyl, R3 is hydrogen and R4 is hydrogen or methyl and being in the (R)-enantiomer form, with a second component (b) which is a selective h5-HT1B antagonist or partial agonist having the formula II wherein X is CH2, O, Y is CONH, NHCO, R1 is H, C1-C6 alky, C3-C6 cycloalkyl, R2 is H, C1-C6 alkyl, C1-C6 alkoxy, halogen, R3 is R4 and R5 independently are H or C1-C4 alkyl as racemate, R-enantiomer or S-enantiomer, and said components (a) and (b) being in the form of free bases, solvates or pharmaceutically acceptable salts thereof, the preparation thereof, pharmaceutical formulations containing said combination, use of and method of treatment of affective disorders such as depression, anxiety and OCD with said combination as well as a kit containing said combination. |
| priorityDate | 1997-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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