| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_977ebb660999f345084ffad260515ff6 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-58 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-787 |
| filingDate |
1998-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_420a3cfba6840f6c62dd9c865d9b2dd1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a21e17d8aded334549fc562f41a21ba0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5cb85e54b66b9cafb41eb66cc84fe67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8a9b23c126f3d7dc471f2aff2edd351
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d47d616d57887f7c524ee1e09177c88 |
| publicationDate |
2003-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-564178-B |
| titleOfInvention |
Polymeric derivatives of camptothecins |
| abstract |
Water soluble polymeric conjugates of camptothecin comprise N-(2-hydroxypropyl) methacryloylamide units linked via a spacer of the formula -Gly-NH-(CH2)n-CO-Gly wherein n=2-8 to the C-20 position of a camptothecin residue. The conjugates possess enhanced antitumor activity and decreased toxicity with respect to the free drug. A process for their preparation and pharmaceutical compositions containing them are also described. |
| priorityDate |
1997-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |