| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D411-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 |
| filingDate |
1999-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c93bf24c583af07b821d4378077879cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_796785387c8e0ffe7a5db4506533533f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c31bbdd6f02c09fd4696eb5da7bb6221
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1802f9a32436678cf4750d2b3f418bf7 |
| publicationDate |
2003-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-555559-B |
| titleOfInvention |
Combinations for the treatment of an HBV infection |
| abstract |
The present invention relates to therapeutic combinations comprising (2R, cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-pyrimidin-2-one (lamivudine) and a second therapeutic agent selected from (9-[(R)-2-(phosphonomethoxy)ethyl]adenine, (PMEA or adefovir) and bis (pivaloyloxymethyl) (9-[(R)-2-(phosphonomethoxy)ethyl]adenine, (the oral prodrug of PMEA, adefovir dipivoxil) which have anti-hepatitis B virus (HBV) activity. The present invention is also concerned with pharmaceutical compositions containing said combinations and their use in the treatment of HBV infections including infections with HBV mutants bearing resistance to nucleoside and/or non-nucleoside inhibitors. |
| priorityDate |
1998-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |