| abstract |
The invention relates to a process for the preparation of ortho-alkylated benzoic acid derivatives of the formula I, characterized in that an aryl bromide of the formula II is reacted with a secondary or tertiary organolithium compound and CO2. Process for the preparation of ortho-alkylated benzoic acid derivatives of the formula I, in which A is an alkyl radical having from 1 to 4 carbon atoms, characterized in that an aryl bromide of the formula II, in which A is as defined in formula I, is reacted with a secondary or tertiary organolithium compound and CO2, wherein the secondary organolithium compound is chosen from the group consisting of sec-butyllithium, isoprpyllithium, sec-amyllithium, 4-heptyllithium, cyclopropyllithium and cyclohexyllithium and the tertiary organolithium compound is tert-butyllithium. |