abstract |
The present invention relates to pharmaceutical compositions comprising a positive modulator of a nicotinic receptor agonist, said positive modulator having the capability to increase the efficacy of the said nicotinic receptor agonist. A pharmaceutical composition comprising a positive modulator of a nicotinic receptor agonist together with a pharmaceutically acceptable carrier, said positive modulator having the capability to increase the efficacy of the said nicotinic receptor agonist; wherein the said positive modulator is 5-hydroxyindole and the said nicotinic receptor agonist is AR-R 17779, which is (-)-spiro[1-azabicyclo[2.2.2]octane-3,5*-oxazolidine]-2*-one. |