http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-541309-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_938a6d7a15cbc93a74abe1953eb25d47 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 1996-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51ac41da625945231449a623f5501b7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_852876bbde5d38d09ae993af804ccc53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_832b12bd3e3cddbc26f340f92588f087 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1dd900c147d36c8174682773a0aa4f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a32adfb9a6925fadc53c831f8f9b4197 |
| publicationDate | 2003-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-541309-B |
| titleOfInvention | Inhibitors of interleukin-1beta converting enzyme |
| abstract | The present invention relates to novel classes of compounds which are inhibitors of interleukin-1beta converting enzyme. The ICE inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting ICE activity and consequently, may be advantageously used as agents against IL-1-, apoptosis-, IGIF-, and IFN-gamma-mediated diseases, inflammatory diseases, autoimmune diseases, destructive bone disorders, proliferative disorders, infectious diseases, degenerative diseases, and necrotic diseases. This invention also relates to pharmaceutical compositions formulated for use in inhibiting ICE activity, for treating interleukin-1-, apoptosis-, IGIF- and IFN-gamma-mediated diseases and decreasing IGIF and IFN-gamma production using the compounds and compositions of this invention. This invention also relates to methods for preparing N-acylamino compounds. |
| priorityDate | 1996-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 805.