http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-533202-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07b71571160c289fbf5fc680dfea513f |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-08 |
filingDate | 1997-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2003-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbbfcc0e46a832965e2c56fcf151df17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af5d705b6744eb199cd31849ae1fbfc3 |
publicationDate | 2003-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-533202-B |
titleOfInvention | Integrin receptor antagonists |
abstract | Compounds of the formula (IV): wherein A1 is C or N; X1-X2 is CHR1-CH, CR1=CH or NR1-CH; X3 is CR5R5', NR5, S(O)u or O; R2 is -OR', -NR'R"", -NR'SO2R""', -NR'OR', -OCR'2C(O)OR', -OCR'2OC(O)-R', -OCR'2C(O)NR'2 or CF3; R3 is H, halo, -OR12, -SR12, -CN, -NR'R12, -NO2, -CF3, CF3S(O)r-, -CO2R', -CONR'2, R14-C0-6alkyl-, R14-C1-6oxoalkyl-, R14-C2-6alkenyl-, R14-C2-6alkynyl-, R14-C0-6alkyloxy-, R14-C0-6alkylamino- or R14-C0-6alkyl-S(O)r-; R6 is W-(CR'2)q-Z-(CR'R10)r-U-(CR'2)s-V- or W'-(CR'2)q-U-(CR'2)s-U and V are absent or CO, CR'2, C(=CR152), S(O)n, O, NR15, CR15'OR15, CR'(OR"")CR'2, CR'2CR'(OR""), C(O)CR'2, CR152C(O), CONR15, NR15CO, OC(O), C(O)O, C(S)O, OC(S), C(S)NR15, NR15C(S), SO2NR15, NR15SO2, N=N, NR15NR15, NR15CR152, CR152O, OCR152, C=C, CR15=CR15, Het, or Ar, provided that U and V are not simultaneously absent; and W and W' are a nitrogen-containing substituent, ane integrin receptor antagonists. |
priorityDate | 1995-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1184.