| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
| filingDate |
1997-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c31c4ae4180646984bf45db2505c3270
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_166b873b8608a595ff4eb5042fb4b7aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a51ba4abead1cd1ba47f08065c70ed76 |
| publicationDate |
2003-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-528802-B |
| titleOfInvention |
Modified thermostable DNA polymerase |
| abstract |
The invention provides thermostable DNA polymerase enzymes that comprises the amino acid sequence SerGlnIleXaaLeuArgXaa (SEQ ID NO: 1), wherein ""Xaa"" at position 4 of this sequence is any amino acid residue but not a glutamic acid residue (Glu), preferably a glycine residue and ""Xaa"" at position 7 of this sequence is a valine residue (Val) or an isoleucine residue (Ile). The thermostable DNA polymerases of the invention have enhanced efficiency for incorporating unconventional nucleotides, such as ribonucleotides, into DNA products and are advantageous in many in vitro synthesis applications. Such enzymes are particularly useful for use in nucleic acid sequencing protocols and provide novel means for DNA sequence analysis with cost and efficiency advantages. Also claimed are nucleic acids encoding said polymerases, vectors and hoste cells comprising such a nucleic acid, as well as compositions for use in a DNA sequencing reaction, kits and methods for sequencing including such polymerases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9309501-B2 |
| priorityDate |
1996-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |