abstract |
Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors. A compound represented by the formula: (I) R1 is a 4-pyridyl, or 4-pyrimidyl ring which is substituted with one C1-4 alkoxy group; R4 is phenyl substituted by halo; R2 is a piperidinyl, which can be substituted by C1-4 alkyl; or a pharmaceutically acceptable salt thereof. |