http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-519543-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_129e393582e6bdf4029baf2206522f45 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-00 |
filingDate | 1998-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2003-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_154d5fc002b9989d3f7e15e08e45c30c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_061c039072354bc48e72b49398fb37e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ae6dc4e27fa0ae62a8233a1c2935d56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a343d91fa41f6487fb9f4adfc22b8e48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dc3ba8922e6f7a743850df1a410fc0f |
publicationDate | 2003-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-519543-B |
titleOfInvention | Quinolinomorphinan derivative and pharmaceutical composition for curing-preventing cerebral disorder |
abstract | This invention relates to a quinolinomorphinane derivative having following formula (I): [wherein R1 represents cyclopropylmethyl etc., R2 and R3 represents hydrogen, or methoxy, etc., and R4 represents hydrogen, methyl or amino, etc., and (R5)m represents hydrogen or substituted benzo, etc.] or a pharmaceutically acceptable acid salt thereof, and a pharmaceutical composition for treating and/or preventing brain damage comprising said derivative. The present compounds provides an advantageous protection against cerebral and nervous cell injury. Since these compounds can inhibit cerebral and nervous cell injury caused by ischemic, hemorrhagic or traumatic cerebral injury or by various neurodegeneration, they can be used in a medicament for the prevention of and/or protection against a variety of cerebral disease, such as cerebral hemorrhage, traumatic cerebral diseases, cerebral edema, and cerebral and nervous degenerative diseases, for improving sequela caused by cerebral diseases and for prevention of the recurrence of the cerebral diseases. |
priorityDate | 1997-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 221.