abstract |
A thiazole compound of the formula: wherein T is C1-C6alkylene; u is 0 or 1; R1 and R2 are the same or different and are each H, or C1-C6alkyl, etc.; R3 is formula; R4 is H or C2-C6alkanoyloxy-C1-C6alkyl, which shows inhibitory activity on protein kinase C(PKC, Ca2+/phospholipid-depending serine/threonine protein phosphatase), and are useful as a protein kinase C inhibitor. |