| abstract |
To obtain a new methoyl-pyrroloindole derivative of antibacterial and anti-tumor activatity, its optical isomers, pharmaceutical acceptable salts, and production intermediates. This carbamoyloxy group-containing compound is shown by formula I [R1 is OH or pyrrolidinyl; (n) is 1 or 2; R2 is a C1-4 lower alkyl group; X-Y or Y-X is CH2, CHOH, CH2-CH2, O-CH2, NMe-CH2; Z is Cl or Br; Ar1 is a group of formula II (Z2, Z3 are O or NH; m is 0 or an integer of 1-4); Ar2 is any of the above mentioned a, b, c or d], its optical isomer and pharmaceutical acceptable salt thereof, and its production intermediate. |