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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fe3d462dc930262fc022b6c0ae7b0d5
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publicationDate 2002-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TW-480265-B
titleOfInvention Method of manufacturing phosphine compound
abstract A method of preparing a compound (I) of general formula (R3-C)2P-L1-X-L2-P-(C-R3)2, in which each R is independently a pendant, optionally substituted, organic group through which the group is linked to tertiary carbon atom C; L1, L2 are independently a linking group selected from an optionally substituted lower alkylene chain connecting the respective phosphorous atom to the group X and X is a bridging group comprising an optionally substituted aryl moiety to which the phosphorous atoms are linked on available adjacent carbon atoms comprises the steps of (i) reacting together a compound (II) of formula A-L1-X-L2-A, in which A is a halogen atom, with a metal M in a suitable solvent to form an intermediate compound (III) of formula A-M-L1-X-L2-M-A, (ii) reacting said intermediate compound (III) with a compound (IV) of formula (R3-C)2P-A1, where A1 is a halogen atom which may be the same as or different form A, to form said compound (I). The compound (I) may be useful to form a catalyst system for the carbonylation of olefins.
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