http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-473478-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0018 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate | 1996-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a25274019bd93e10ed15f781f6c4adf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_204d4933b0a4d012218ce1e4a40900c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd7eec6b55be0ba2b1000d535090fb63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fded124fbcc8ecb443a70970258f34b |
| publicationDate | 2002-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-473478-B |
| titleOfInvention | Camptothecin derivatives, the process for preparing thereof and the use |
| abstract | A camptothecin derivative comprising a compound of the formula [I]: wherein R1, R2, R3, R4, and R5, are (A) adjacent two groups combine to form alkylene, or both are H, and one of the remaining three groups is -Xn-Alkm-R6, and the other two are H, alkyl or halogen, or (B) adjacent two groups combine to form alkylene, and one of the carbon atoms of said alkylene group is substituted by -Xn-Alkm-R6, and the remaining three groups are H, alkyl or a halogen, and one or two -CH2- of the alkylene in (A) or (B) may optionally be replaced by -O-, -S- or -NH-, X is -O- or -NH-, Alk is alkylene, R6 is -NH2, -N-NH, or -OH, m and n are both 0 or 1, or m is 1 and n is 0, which camptothecin compound is bound to a polysaccharide having carboxyl groups via an amino acid or a peptide, or a pharmaceutically acceptable salt thereof. Said camptothecin derivatives show enhanced antitumor activities but few side effects and are useful as a medicament. |
| priorityDate | 1995-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 186.