| abstract |
The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of formula I and pyrimidine-thioalkyl and alkylethers of formula IA, namely the compounds of formula I where R4 is selected from the group consisting of -H or -NR15R16 where R15 is -H and R16 is -H, C1-C6 alkyl, -NH2 or R15 and R16 taken together with the -N form 1-pyrrolidino, 1-morpholino or 1-piperidino; and R6 is selected from the group consisting of -H, or halo (preferably -C1); with the overall provisio that R4 and R6 are not both -H. The compounds of formula IA are useful in the treatment of individuals who are HIV positive. |