abstract |
Kainic acid nerve cytoxic inhibitor and pyridothiazine derivative of the formula (I), (wherein A ring: pyridine ring R1-R5: same or different, H, unsubstituted or substituted lower alkyl, cycloalkyl, alkenyl, aryl, carboxyl, lower alkoxycarbonyl, or absent, or R2 and R3 formed together an N containing heterocycle may have another N as hetero atom, maybe condensed with benzene ring and maybe substituted with lower alkyl) and the pharmaceutical acceptable salt thereof. |