abstract |
Compounds useful in the preparation of pharmaceutical preparations for the treatment of microbial infection where such compounds are of structural formula I, or pharmaceutically acceptable salts thereof wherein: R1 is -CHO, -COCH3, -COCHCl2, -COCHF2, -CO2CH3, -SO2CH3, or -COCH2OH; X1 and X2 are independently H, F, or Cl and Q is a five membered ring heterocycle (azolyl ring) of the general form: wherein A, B, and C are indepedently oxygen (O), nitrogen (N), sulfur (S) or carbon (C). In all cases, the piperazine nitrogen atom is attached at the carbon atom of the carbon-nitrogen double bond. |